Immunoproteasome subunit β5i promotes perifascicular muscle atrophy in dermatomyositis by upregulating RIG-I

Background Perifascicular atrophy is a unique pathological hallmark in dermatomyositis (DM)-affected muscles; however, the mechanism underlying this process remains unclear. In this study, we aimed to investigate the potential role of the immunoproteasome subunit β5i and retinoic acid-inducible gene...

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Bibliographic Details
Main Authors: Lu Zhang, Wenli Li, Xiaolan Tian, Guochun Wang, Qinglin Peng, Lifang Ye, Qisheng Xia, Qingyan Liu, Lining Zhang
Format: Article
Language:English
Published: BMJ Publishing Group 2023-02-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/9/1/e002818.full