Introducing difference recurrence relations for faster semi-global alignment of long sequences
Abstract Background The read length of single-molecule DNA sequencers is reaching 1 Mb. Popular alignment software tools widely used for analyzing such long reads often take advantage of single-instruction multiple-data (SIMD) operations to accelerate calculation of dynamic programming (DP) matrices...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-02-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-018-2014-8 |