Canonical androgen response element motifs are tumor suppressive regulatory elements in the prostate

Canonical androgen response element motifs are tumor suppressive regulatory elements in the prostate

Abstract The androgen receptor (AR) is central in prostate tissue identity and differentiation, and controls normal growth-suppressive, prostate-specific gene expression. It also drives prostate tumorigenesis when hijacked for oncogenic transcription. The execution of growth-suppressive AR transcrip...

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Bibliographic Details
Main Authors: Xuanrong Chen, Michael A. Augello, Deli Liu, Kevin Lin, Alex Hakansson, Martin Sjöström, Francesca Khani, Lesa D. Deonarine, Yang Liu, Jaida Travascio-Green, Jiansheng Wu, Un In Chan, Jude Owiredu, Massimo Loda, Felix Y. Feng, Brian D. Robinson, Elai Davicioni, Andrea Sboner, Christopher E. Barbieri
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53734-z

Internet

https://doi.org/10.1038/s41467-024-53734-z

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