Discovery of 1-(5-bromopyrazin-2-yl)-1-[3-(trifluoromethyl)benzyl]urea as a promising anticancer drug via synthesis, characterization, biological screening, and computational studies

Discovery of 1-(5-bromopyrazin-2-yl)-1-[3-(trifluoromethyl)benzyl]urea as a promising anticancer drug via synthesis, characterization, biological screening, and computational studies

Abstract Cancer and different types of tumors are still the most resistant diseases to available therapeutic agents. Finding a highly effective anticancer drug is the first target and concern of thousands of drug designers. In our attempts to address this concern, a new pyrazine derivative, 1-(5-bro...

Full description

Bibliographic Details
Main Authors: Yasser Hussein Issa Mohammed, Israa M. Shamkh, Nahed S. Alharthi, Mohammed A. Shanawaz, Hind A. Alzahrani, Basit Jabbar, Saba Beigh, Saad Alghamdi, Nada Alsakhen, Elshiekh B. Khidir, Hayaa M. Alhuthali, Taqwa Hafiz Elamin Karamalla, Amgad M. Rabie
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-44662-x

Internet

https://doi.org/10.1038/s41598-023-44662-x

Similar Items