Efficacy and safety evaluation of Azvudine in the prospective treatment of COVID-19 based on four phase III clinical trials

Efficacy and safety evaluation of Azvudine in the prospective treatment of COVID-19 based on four phase III clinical trials

Azvudine (FNC) is a synthetic nucleoside analog used to treat adult patients living with human immunodeficiency virus-1 (HIV-1) infection with high viral load. After phosphorylation, Azvudine inhibits RNA-dependent RNA polymerase, leading to the discontinuation of RNA chain synthesis in viruses. In...

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Bibliographic Details
Main Author: Ke-Wei Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Pharmacology
Subjects:
Azvudine (FNC)
viral load
severe acute respiratory syndrome coronavirus 2
RNA-dependent RNA polymerase
nucleic acid-negative conversion time
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1228548/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1228548/full

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