NITRIC OXIDE INTERFERES WITH HYPOXIA SIGNALING DURING COLONIC INFLAMMATION

NITRIC OXIDE INTERFERES WITH HYPOXIA SIGNALING DURING COLONIC INFLAMMATION

Context Intestinal inflammation can induce a local reduction in oxygen levels that triggers an adaptive response centered on the expression of hypoxia-inducible factors (HIFs). Nitric oxide, a well-described inflammatory mediator, may interfere with hypoxia signaling. Objectives We aimed to evalua...

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Bibliographic Details
Main Authors: Cintia Rabelo e Paiva CARIA, Camila Henrique MOSCATO, Renata Bortolin Guerra TOMÉ, José PEDRAZZOLI Jr, Marcelo Lima RIBEIRO, Alessandra GAMBERO
Format: Article
Language:English
Published: Instituto Brasileiro de Estudos e Pesquisas de Gastroenterologia (IBEPEGE) 2014-12-01
Series:Arquivos de Gastroenterologia
Subjects:
Colite
Fator 1 induzível por hipóxia
Óxido nítrico
NG-Nitroarginina metil éster
Fatores de crescimento endotelial
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-28032014000400302&lng=en&tlng=en

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