Dual Functioned Hexapeptide‐Coated Lipid‐Core Nanomicelles Suppress Toll‐Like Receptor‐Mediated Inflammatory Responses through Endotoxin Scavenging and Endosomal pH Modulation

Dual Functioned Hexapeptide‐Coated Lipid‐Core Nanomicelles Suppress Toll‐Like Receptor‐Mediated Inflammatory Responses through Endotoxin Scavenging and Endosomal pH Modulation

Abstract Excessive activation of Toll‐like receptor (TLR) signaling pathways and the circulating endotoxin are key players in the pathogenesis of many acute and chronic inflammatory diseases. Regulation of TLR‐mediated inflammatory responses by bioactive nanodevices represents a promising strategy f...

Full description

Bibliographic Details
Main Authors: Yuting Ji, Liya Sun, Yuan Liu, Yanhui Li, Tongxuan Li, Jiameng Gong, Xiali Liu, Huiqiang Ma, Jingying Wang, Bing Chen, Shan‐Yu Fung, Hong Yang
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Advanced Science
Subjects:
acute lung injury
endotoxin scavenger
lipid nanomicelle
macrophage
nano‐therapy
Toll‐like receptor
Online Access:https://doi.org/10.1002/advs.202301230

Internet

https://doi.org/10.1002/advs.202301230

Similar Items