TIMP1 and TIMP2 Downregulate TGFβ Induced Decidual-like Phenotype in Natural Killer Cells

TIMP1 and TIMP2 Downregulate TGFβ Induced Decidual-like Phenotype in Natural Killer Cells

Natural Killer (NK) cells have been found to be anergic, exhausted and pro-angiogenic in cancers. NK cell from healthy donors, exposed to TGFβ, acquire the CD56<sup>bright</sup>CD9<sup>+</sup>CD49a<sup>+</sup> decidual-like-phenotype, together with decreased level...

Full description

Bibliographic Details
Main Authors: Adriana Albini, Matteo Gallazzi, Maria Teresa Palano, Valentina Carlini, Riccardo Ricotta, Antonino Bruno, William G. Stetler-Stevenson, Douglas M. Noonan
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
TIMP-1
TIMP-2
TGFβ
Natural Killer cells
decidual-NK cells
tumor microenvironment
Online Access:https://www.mdpi.com/2072-6694/13/19/4955

Internet

https://www.mdpi.com/2072-6694/13/19/4955

Similar Items