Experimental Validation and Prediction of Super-Enhancers: Advances and Challenges

Experimental Validation and Prediction of Super-Enhancers: Advances and Challenges

Super-enhancers (SEs) are cis-regulatory elements of the human genome that have been widely discussed since the discovery and origin of the term. Super-enhancers have been shown to be strongly associated with the expression of genes crucial for cell differentiation, cell stability maintenance, and t...

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Bibliographic Details
Main Authors: Ekaterina V. Kravchuk, German A. Ashniev, Marina G. Gladkova, Alexey V. Orlov, Anastasiia V. Vasileva, Anna V. Boldyreva, Alexandr G. Burenin, Artemiy M. Skirda, Petr I. Nikitin, Natalia N. Orlova
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Cells
Subjects:
super-enhancer
chromatin looping
therapy
regulation
experimental validation
drugs targeting chromatin interactions
Online Access:https://www.mdpi.com/2073-4409/12/8/1191

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https://www.mdpi.com/2073-4409/12/8/1191

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