Silence of HOTAIR promotes osteogenic differentiation and accelerates distraction osteogenesis by mediating FTO ubiquitination

Silence of HOTAIR promotes osteogenic differentiation and accelerates distraction osteogenesis by mediating FTO ubiquitination

Background: Distraction osteogenesis(DO) is a valuable bone regeneration technique, yet its prolonged consolidation phase often entails pain, high costs, infection risks, and lifestyle disruptions. Finding adjunctive approaches to shorten treatment duration is thus of clinical significance. Long non...

Full description

Bibliographic Details
Main Authors: Xiao-min Wu, Yong-xin Mai, Yong-fa Wen, Zhi-peng Li, Yu-xin Sun, Jun-jing Chen, Fengzhen Meng, feng-xiang Pang, Huai-ming Li, Yu Pan, Jin-fang Zhang, Xiao-hua Pan
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Orthopaedic Translation
Subjects:
Distraction osteogenesis
FTO
HOTAIR
Osteogenesis
Ubiquitination
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X24001608

Internet

http://www.sciencedirect.com/science/article/pii/S2214031X24001608

Similar Items