NSG Mice Facilitate ex vivo Characterization of Ewing Sarcoma Lung Metastasis Using the PuMA Model

NSG Mice Facilitate ex vivo Characterization of Ewing Sarcoma Lung Metastasis Using the PuMA Model

Ewing sarcoma (EwS) is a highly malignant bone and soft tissue tumor primarily affecting children and young adults. While most patients initially respond well to conventional front-line therapy, frequent metastasis results in poor 5-year overall survival rates for this disease. Accordingly, there is...

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Bibliographic Details
Main Authors: Renata Scopim-Ribeiro, Michael M. Lizardo, Hai-Feng Zhang, Anne-Chloé Dhez, Chistopher S. Hughes, Poul H. Sorensen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
lung metastasis
Ewing sarcoma
osteosarcoma
PuMA
NSG mice
NK cells
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.645757/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.645757/full

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