Heterologous booster with a novel formulation containing glycosylated trimeric S protein is effective against Omicron

Heterologous booster with a novel formulation containing glycosylated trimeric S protein is effective against Omicron

In this study, we evaluated the efficacy of a heterologous three-dose vaccination schedule against the Omicron BA.1 SARS-CoV-2 variant infection using a mouse intranasal challenge model. The vaccination schedules tested in this study consisted of a primary series of 2 doses covered by two commercial...

Full description

Bibliographic Details
Main Authors: Daniela Bottero, Erika Rudi, Pablo Martin Aispuro, Eugenia Zurita, Emilia Gaillard, Maria M. Gonzalez Lopez Ledesma, Juan Malito, Matthew Stuible, Nicolas Ambrosis, Yves Durocher, Andrea V. Gamarnik, Andrés Wigdorovitz, Daniela Hozbor
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Immunology
Subjects:
spike-based vaccine
SARS- CoV-2
Omicron
heterologous booster
COVID-19
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1271209/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1271209/full

Similar Items