Paraquat induces oxidative stress, neuronal loss in substantia nigra region and Parkinsonism in adult rats: Neuroprotection and amelioration of symptoms by water-soluble formulation of Coenzyme Q<sub>10</sub>

<p>Abstract</p> <p>Background</p> <p>Parkinson's disease, for which currently there is no cure, develops as a result of progressive loss of dopamine neurons in the brain; thus, identification of any potential therapeutic intervention for disease management is of a...

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Bibliographic Details
Main Authors: Sridhar TS, Sikorska Marianna, Cohen Jerome, Sandhu Jagdeep K, Somayajulu-Niţu Mallika, Matei Anca, Borowy-Borowski Henryk, Pandey Siyaram
Format: Article
Language:English
Published: BMC 2009-07-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/10/88