Chemerin-Induced Down-Regulation of Placenta-Derived Exosomal miR-140-3p and miR-574-3p Promotes Umbilical Vein Endothelial Cells Proliferation, Migration, and Tube Formation in Gestational Diabetes Mellitus

Chemerin-Induced Down-Regulation of Placenta-Derived Exosomal miR-140-3p and miR-574-3p Promotes Umbilical Vein Endothelial Cells Proliferation, Migration, and Tube Formation in Gestational Diabetes Mellitus

Gestational diabetes mellitus (GDM) leads to poor pregnancy outcomes and fetoplacental endothelial dysfunction; however, the underlying mechanisms remain unknown. This study aimed to investigate the effect of placenta-derived exosomal miRNAs on fetoplacental endothelial dysfunction in GDM, as well a...

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Bibliographic Details
Main Authors: Lixia Zhang, Qi Wu, Shuqi Zhu, Yibo Tang, Yanmin Chen, Danqing Chen, Zhaoxia Liang
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
placenta-derived exosomal miRNAs
chemerin
umbilical vein endothelial cells
gestational diabetes mellitus
Online Access:https://www.mdpi.com/2073-4409/11/21/3457

Internet

https://www.mdpi.com/2073-4409/11/21/3457

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