Integrative Kinase Activity Profiling and Phosphoproteomics of <i>rd10</i> Mouse Retina during cGMP-Dependent Retinal Degeneration

Integrative Kinase Activity Profiling and Phosphoproteomics of <i>rd10</i> Mouse Retina during cGMP-Dependent Retinal Degeneration

Inherited retinal degenerative diseases (IRDs) are a group of rare diseases that lead to a progressive loss of photoreceptor cells and, ultimately, blindness. The overactivation of cGMP-dependent protein kinase G (PKG), one of the key effectors of cGMP-signaling, was previously found to be involved...

Full description

Bibliographic Details
Main Authors: Akanksha Roy, Jiaming Zhou, Merijn Nolet, Charlotte Welinder, Yu Zhu, François Paquet-Durand, John Groten, Tushar Tomar, Per Ekström
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
<i>rd10</i>
PKG
CREB
CaMK
phosphoproteomics
kinome activity profiling
Online Access:https://www.mdpi.com/1422-0067/25/6/3446

Internet

https://www.mdpi.com/1422-0067/25/6/3446

Similar Items