H1N1 influenza virus dose dependent induction of dysregulated innate immune responses and STAT1/3 activation are associated with pulmonary immunopathological damage

H1N1 influenza virus dose dependent induction of dysregulated innate immune responses and STAT1/3 activation are associated with pulmonary immunopathological damage

Influenza A virus (IAV) infection poses a substantial challenge and causes high morbidity and mortality. Exacerbated pulmonary inflammatory responses are the major causes of extensive diffuse alveolar immunopathological damage. However, the relationship between the extent of cytokine storm, neutroph...

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Bibliographic Details
Main Authors: Duoduo Yao, Linlin Bao, Fengdi Li, Bo Liu, Xu Wu, Ziqi Hu, Jiangnan Xu, Wei Wang, Xulong Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Virulence
Subjects:
STAT1
STAT3
acute lung injury
H1N1
innate immune
viral pneumonia
Online Access:https://www.tandfonline.com/doi/10.1080/21505594.2022.2120951

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https://www.tandfonline.com/doi/10.1080/21505594.2022.2120951

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