Antioxidant Activity, Molecular Docking, Quantum Studies and In Vivo Antinociceptive Activity of Sulfonamides Derived From Carvacrol

Antioxidant Activity, Molecular Docking, Quantum Studies and In Vivo Antinociceptive Activity of Sulfonamides Derived From Carvacrol

The synthesis and antioxidant, antinociceptive and antiedematogenic activities of sulfonamides derived from carvacrol—a druglike natural product—are reported. The compounds showed promising antioxidant activity, and sulfonamide derived from morpholine (S1) demonstrated excellent antinociceptive and...

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Bibliographic Details
Main Authors: Aldo S. de Oliveira, Luana C. Llanes, Ricardo J. Nunes, Catharina Nucci-Martins, Anacleto S. de Souza, David L. Palomino-Salcedo, María J. Dávila-Rodríguez, Leonardo L. G. Ferreira, Adair R. S. Santos, Adriano D. Andricopulo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
sulfonamides
pain
carvacrol
molecular modeling
antioxidant
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.788850/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.788850/full

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