Study protocol for the Heads-Up trial: a phase II randomized controlled trial investigating head-up tilt sleeping to alleviate orthostatic intolerance in Parkinson’s Disease and parkinsonism

Abstract Background In persons with Parkinson’s Disease (PD) or certain forms of atypical parkinsonism, orthostatic hypotension is common and disabling, yet often underrecognized and undertreated. About half of affected individuals also exhibit supine hypertension. This common co-occurrence of both...

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Main Authors: Amber H. van der Stam, Nienke M. de Vries, Sharon Shmuely, Daan Smeenk, Joost H. Rutten, Ineke A. van Rossum, Susanne T. de Bot, Jurgen A. Claassen, Bastiaan R. Bloem, Roland D. Thijs
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Neurology
Subjects:
Online Access:https://doi.org/10.1186/s12883-023-03506-x