Polyethylene glycol glucose conjugate: an enabling excipient to block overexpressed glucose transporters on malignant cells

A commonality between many cancers is that they have increased rates of glucose uptake that is, in turn, achieved by overexpression of cell membrane localized uniporters called glucose transporters or GLUT. A 'near universal' approach to kill cancer cells lies in depriving them of their me...

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Bibliographic Details
Main Author: Shireesh Apte
Format: Article
Language:English
Published: International Pharmaceutical Excipients Council 2016-09-01
Series:Journal of Excipients and Food Chemicals
Online Access:https://jefc.scholasticahq.com/article/922-polyethylene-glycol-glucose-conjugate-an-enabling-excipient-to-block-overexpressed-glucose-transporters-on-malignant-cells