Polyethylene glycol glucose conjugate: an enabling excipient to block overexpressed glucose transporters on malignant cells
A commonality between many cancers is that they have increased rates of glucose uptake that is, in turn, achieved by overexpression of cell membrane localized uniporters called glucose transporters or GLUT. A 'near universal' approach to kill cancer cells lies in depriving them of their me...
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Format: | Article |
Language: | English |
Published: |
International Pharmaceutical Excipients Council
2016-09-01
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Series: | Journal of Excipients and Food Chemicals |
Online Access: | https://jefc.scholasticahq.com/article/922-polyethylene-glycol-glucose-conjugate-an-enabling-excipient-to-block-overexpressed-glucose-transporters-on-malignant-cells |