An Efficient Method for the Preparation of N-Formamides using Propylphosphonic Anhydride (T3P®)
Abstract The synthesis of N-formamides from aromatic amines and formic acid using propylphosphonic anhydride (T3P®) as a green coupling reagent is described. By using this method, aryl, heteroaryl and fluorinated aryl-containing formamides were synthesized in high yield and purity. The significant f...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Georg Thieme Verlag KG
2018-04-01
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| Series: | SynOpen |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0036-1591584 |