Structure, Function, and Therapeutic Use of IgM Antibodies

Natural immunoglobulin M (IgM) antibodies are pentameric or hexameric macro-immunoglobulins and have been highly conserved during evolution. IgMs are initially expressed during B cell ontogeny and are the first antibodies secreted following exposure to foreign antigens. The IgM multimer has either 1...

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Bibliographic Details
Main Authors: Bruce A. Keyt, Ramesh Baliga, Angus M. Sinclair, Stephen F. Carroll, Marvin S. Peterson
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Antibodies
Subjects:
Online Access:https://www.mdpi.com/2073-4468/9/4/53