Identification of TIGAR in the equilibrative nucleoside transporter 2-mediated response to fludarabine in chronic lymphocytic leukemia cells
Background The nucleoside analogue fludarabine is used in the treatment of chronic lymphocytic leukemia. It triggers p53-mediated apoptosis, although the mutational status of p53 does not fully account for heterogeneity in responsiveness to treatment. The aim of this study was to identify new genes...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Ferrata Storti Foundation
2008-12-01
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Series: | Haematologica |
Online Access: | https://haematologica.org/article/view/5108 |