Identification of TIGAR in the equilibrative nucleoside transporter 2-mediated response to fludarabine in chronic lymphocytic leukemia cells

Background The nucleoside analogue fludarabine is used in the treatment of chronic lymphocytic leukemia. It triggers p53-mediated apoptosis, although the mutational status of p53 does not fully account for heterogeneity in responsiveness to treatment. The aim of this study was to identify new genes...

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Bibliographic Details
Main Authors: Mónica López-Guerra, Laia Trigueros-Motos, Miriam Molina-Arcas, Neus Villamor, F. Javier Casado, Emili Montserrat, Elias Campo, Dolors Colomer, Marçal Pastor-Anglada
Format: Article
Language:English
Published: Ferrata Storti Foundation 2008-12-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/5108