Neo-intline: integrated pipeline enables neoantigen design through the in-silico presentation of T-cell epitope

Abstract Neoantigen vaccines are one of the most effective immunotherapies for personalized tumour treatment. The current immunogen design of neoantigen vaccines is usually based on whole-genome sequencing (WGS) and bioinformatics prediction that focuses on the prediction of binding affinity between...

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Bibliographic Details
Main Authors: Bingyu Li, Ping Jing, Genhui Zheng, Chenyu Pi, Lu Zhang, Zuojing Yin, Lijun Xu, Jingxuan Qiu, Hua Gu, Tianyi Qiu, Jianmin Fang
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-023-01644-9