Lack of Charge Interaction in the Ion Binding Site Determines Anion Selectivity in the Sodium Bicarbonate Cotransporter NBCe1

The Na/HCO<sub>3</sub> cotransporter NBCe1 is a member of SLC4A transporters that move HCO<sub>3</sub><sup>−</sup> across cell membranes and regulate intracellular pH or transepithelial HCO<sub>3</sub> transport. NBCe1 is highly selective to HCO<sub...

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Bibliographic Details
Main Authors: Soojung Lee, Jason Lin, Inyeong Choi
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/1/532