Iron Chelators and Antioxidants Regenerate Neuritic Tree and Nigrostriatal Fibers of MPP+/MPTP-Lesioned Dopaminergic Neurons.

Iron Chelators and Antioxidants Regenerate Neuritic Tree and Nigrostriatal Fibers of MPP+/MPTP-Lesioned Dopaminergic Neurons.

Neuronal death in Parkinson's disease (PD) is often preceded by axodendritic tree retraction and loss of neuronal functionality. The presence of non-functional but live neurons opens therapeutic possibilities to recover functionality before clinical symptoms develop. Considering that iron accum...

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Bibliographic Details
Main Authors: Pabla Aguirre, Natalia P Mena, Carlos M Carrasco, Yorka Muñoz, Patricio Pérez-Henríquez, Rodrigo A Morales, Bruce K Cassels, Carolina Méndez-Gálvez, Olimpo García-Beltrán, Christian González-Billault, Marco T Núñez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0144848&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0144848&type=printable

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