Physiological role of Kv1.3 channel in T lymphocyte cell investigated quantitatively by kinetic modeling.

Physiological role of Kv1.3 channel in T lymphocyte cell investigated quantitatively by kinetic modeling.

Kv1.3 channel is a delayed rectifier channel abundant in human T lymphocytes. Chronic inflammatory and autoimmune disorders lead to the over-expression of Kv1.3 in T cells. To quantitatively study the regulatory mechanism and physiological function of Kv1.3 in T cells, it is necessary to have a prec...

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Bibliographic Details
Main Authors: Panpan Hou, Rong Zhang, Yongfeng Liu, Jing Feng, Wei Wang, Yingliang Wu, Jiuping Ding
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3940720?pdf=render

Internet

http://europepmc.org/articles/PMC3940720?pdf=render

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