The impact of methodology on the reproducibility and rigor of DNA methylation data

The impact of methodology on the reproducibility and rigor of DNA methylation data

Abstract Epigenetic modifications are crucial for normal development and implicated in disease pathogenesis. While epigenetics continues to be a burgeoning research area in neuroscience, unaddressed issues related to data reproducibility across laboratories remain. Separating meaningful experimental...

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Bibliographic Details
Main Authors: Detlev Boison, Susan A. Masino, Farah D. Lubin, Kai Guo, Theresa Lusardi, Richard Sanchez, David N. Ruskin, Joyce Ohm, Jonathan D. Geiger, Junguk Hur
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-04346-w

Internet

https://doi.org/10.1038/s41598-021-04346-w

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