The impact of methodology on the reproducibility and rigor of DNA methylation data
Abstract Epigenetic modifications are crucial for normal development and implicated in disease pathogenesis. While epigenetics continues to be a burgeoning research area in neuroscience, unaddressed issues related to data reproducibility across laboratories remain. Separating meaningful experimental...
Main Authors: | Detlev Boison, Susan A. Masino, Farah D. Lubin, Kai Guo, Theresa Lusardi, Richard Sanchez, David N. Ruskin, Joyce Ohm, Jonathan D. Geiger, Junguk Hur |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-01-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-04346-w |
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