Harnessing Radiation Biology to Augment Immunotherapy for Glioblastoma

Harnessing Radiation Biology to Augment Immunotherapy for Glioblastoma

Glioblastoma is the most common adult primary brain tumor and carries a dismal prognosis. Radiation is a standard first-line therapy, typically deployed following maximal safe surgical debulking, when possible, in combination with cytotoxic chemotherapy. For other systemic cancers, standard of care...

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Bibliographic Details
Main Authors: Karishma R. Rajani, Lucas P. Carlstrom, Ian F. Parney, Aaron J. Johnson, Arthur E. Warrington, Terry C. Burns
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Oncology
Subjects:
radiation
glioblastoma
GBM
PD-1/PD-L1
CTLA-4
immunotherapies
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00656/full

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https://www.frontiersin.org/article/10.3389/fonc.2018.00656/full

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