Treatment of Human Glioblastoma with a Live Attenuated Zika Virus Vaccine Candidate

Treatment of Human Glioblastoma with a Live Attenuated Zika Virus Vaccine Candidate

ABSTRACT Glioblastoma (GBM) is the deadliest type of brain tumor, and glioma stem cells (GSCs) contribute to tumor recurrence and therapeutic resistance. Thus, an oncolytic virus targeting GSCs may be useful for improving GBM treatment. Because Zika virus (ZIKV) has an oncolytic tropism for infectin...

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Bibliographic Details
Main Authors: Qi Chen, Jin Wu, Qing Ye, Feng Ma, Qian Zhu, Yan Wu, Chao Shan, Xuping Xie, Dapei Li, Xiaoyan Zhan, Chunfeng Li, Xiao-Feng Li, Xiaoling Qin, Tongyan Zhao, Haitao Wu, Pei-Yong Shi, Jianghong Man, Cheng-Feng Qin
Format: Article
Language:English
Published: American Society for Microbiology 2018-11-01
Series:mBio
Subjects:
Zika virus
anticancer therapy
glioblastoma
vaccine
Online Access:https://journals.asm.org/doi/10.1128/mBio.01683-18

Internet

https://journals.asm.org/doi/10.1128/mBio.01683-18

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