Ethyl (1R*,10S*,12R*,15S*)-4-Hydroxy-2-oxo-15- (2-oxo-1-pyrrolidinyl)-9-oxatetracyclo[10.2.2.01,10.03,8]hexadeca-3,5,7,13-tetraene-13-carboxylate

Ethyl (1R*,10S*,12R*,15S*)-4-Hydroxy-2-oxo-15- (2-oxo-1-pyrrolidinyl)-9-oxatetracyclo[10.2.2.01,10.03,8]hexadeca-3,5,7,13-tetraene-13-carboxylate

N-Vinylpirrolidinone reacts with (E)-ethyl 5-hydroxy-3-(4-oxo-4H-chromen-3-yl) acrylate (1) through a domino reaction similar to that reported reaction for ethyl vinyl ether. Inverse electron demand Diels–Alder (IEDDA)–elimination-IEDDA generates isomeric tetracycles 5 and 6. The assignment of the r...

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Bibliographic Details
Main Authors: Jorge Heredia-Moya, Ramiro Araya-Maturana
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Molbank
Subjects:
domino-reaction
inverse electron demand Diels–Alder
N-vinylpyrrolidinone
chromone derivatives
Online Access:http://www.mdpi.com/1422-8599/2017/1/M928

Internet

http://www.mdpi.com/1422-8599/2017/1/M928

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