Ex Vivo Infection of Human Placental Explants by <i>Trypanosoma cruzi</i> Reveals a microRNA Profile Similar to That Seen in Trophoblast Differentiation

Ex Vivo Infection of Human Placental Explants by <i>Trypanosoma cruzi</i> Reveals a microRNA Profile Similar to That Seen in Trophoblast Differentiation

Congenital Chagas disease, caused by the protozoan parasite <i>Trypanosoma cruzi</i>, is responsible for 22.5% of new cases each year. However, placental transmission occurs in only 5% of infected mothers and it has been proposed that the epithelial turnover of the trophoblast can be con...

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Bibliographic Details
Main Authors: Lisvaneth Medina, Jesús Alejandro Guerrero-Muñoz, Ana Isabel Liempi, Christian Castillo, Yessica Ortega, Alfredo Sepúlveda, Fernando Salomó, Juan Diego Maya, Ulrike Kemmerling
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Pathogens
Subjects:
<i>Trypanosoma cruzi</i>
miRNAs
placenta
trophoblast differentiation
Online Access:https://www.mdpi.com/2076-0817/11/3/361

Internet

https://www.mdpi.com/2076-0817/11/3/361

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