CHFR and Paclitaxel Sensitivity of Ovarian Cancer

CHFR and Paclitaxel Sensitivity of Ovarian Cancer

The poly(ADP-ribose) binding protein CHFR regulates cellular responses to mitotic stress. The deubiquitinase UBC13, which regulates CHFR levels, has been associated with better overall survival in paclitaxel-treated ovarian cancer. Despite the extensive use of taxanes in the treatment of ovarian can...

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Bibliographic Details
Main Authors: Andrea E. Wahner Hendrickson, Daniel W. Visscher, Xiaonan Hou, Krista M. Goergen, Hunter J. Atkinson, Thomas G. Beito, Vivian Negron, Wilma L. Lingle, Amy K. Bruzek, Rachel M. Hurley, Jill M. Wagner, Karen S. Flatten, Kevin L. Peterson, Paula A. Schneider, Melissa C. Larson, Matthew J. Maurer, Kimberly R. Kalli, Ann L. Oberg, S. John Weroha, Scott H. Kaufmann
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cancers
Subjects:
CHFR
ovarian cancer
taxanes
patient-derived xenografts
Online Access:https://www.mdpi.com/2072-6694/13/23/6043

Internet

https://www.mdpi.com/2072-6694/13/23/6043

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