Enhanced tumor cell killing by ultrasound after microtubule depolymerization

Enhanced tumor cell killing by ultrasound after microtubule depolymerization

Abstract Recent studies show that tumor cells are vulnerable to mechanical stresses and undergo calcium‐dependent apoptosis (mechanoptosis) with mechanical perturbation by low‐frequency ultrasound alone. To determine if tumor cells are particularly sensitive to mechanical stress in certain phases of...

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Bibliographic Details
Main Authors: Aditi Singh, Ajay Tijore, Felix Margadant, Chloe Simpson, Deepak Chitkara, Boon Chuan Low, Michael Sheetz
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Bioengineering & Translational Medicine
Subjects:
apoptosis
cancer therapy
mechanical forces
microtubules
Piezo1
ultrasound
Online Access:https://doi.org/10.1002/btm2.10233

Internet

https://doi.org/10.1002/btm2.10233

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