Identification of Novel Biallelic TLE6 Variants in Female Infertility With Preimplantation Embryonic Lethality

Identification of Novel Biallelic TLE6 Variants in Female Infertility With Preimplantation Embryonic Lethality

Preimplantation embryonic lethality is a rare cause of primary female infertility. It has been reported that variants in the transducin-like enhancer of split 6 (TLE6) gene can lead to preimplantation embryonic lethality. However, the incidence of TLE6 variants in patients with preimplantation embry...

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Bibliographic Details
Main Authors: Manyu Zhang, Chunyu Liu, Beili Chen, Mingrong Lv, Huijuan Zou, Yajing Liu, Yang Gao, Tianjuan Wang, Qiong Xing, Yutong Zhu, Huan Wu, Zhiguo Zhang, Ping Zhou, Zhaolian Wei, Xiaojin He, Yuping Xu, Yunxia Cao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Genetics
Subjects:
preimplantation embryonic lethality
transducin-like enhancer of split 6 (TLE6)
variant
whole-exome sequencing
oocyte donation
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.666136/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.666136/full

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