Mesenchymal Stem Cells Antagonize IFN-Induced Proinflammatory Changes and Growth Inhibition Effects via Wnt/β-Catenin and JAK/STAT Pathway in Human Outer Root Sheath Cells and Hair Follicles

Mesenchymal Stem Cells Antagonize IFN-Induced Proinflammatory Changes and Growth Inhibition Effects via Wnt/β-Catenin and JAK/STAT Pathway in Human Outer Root Sheath Cells and Hair Follicles

Mesenchymal stem cell therapy (MSCT) has been shown to be a new therapeutic option for treating alopecia areata (AA). Outer root sheath cells (ORSCs) play key roles in maintaining the hair follicle structure and supporting the bulge area. In human ORSCs (hORSCs), the mechanism for this process has n...

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Bibliographic Details
Main Authors: Yu-Jin Lee, Song-Hee Park, Hye-Ree Park, Young Lee, Hoon Kang, Jung-Eun Kim
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
mesenchymal stem cell therapy
Wnt/β-catenin pathway
JAK/STAT pathway
hair follicle
outer root sheath cells
Online Access:https://www.mdpi.com/1422-0067/22/9/4581

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https://www.mdpi.com/1422-0067/22/9/4581

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