Iron homeostasis in a mouse model of thalassemia intermedia is altered between adolescence and adulthood
Background Iron overload is one of common complications of β-thalassemia. Systemic iron homeostasis is regulated by iron-regulatory hormone, hepcidin, which inhibits intestinal iron absorption and iron recycling by reticuloendothelial system. In addition, body iron status and requirement can be alte...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2020-03-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/8802.pdf |