Combinatorial Microgels for 3D ECM Screening and Heterogeneous Microenvironmental Culture of Primary Human Hepatic Stellate Cells

Abstract Nonalcoholic fatty liver disease affects 30% of the United States population and its progression can lead to nonalcoholic steatohepatitis (NASH), and increased risks for cirrhosis and hepatocellular carcinoma. NASH is characterized by a highly heterogeneous liver microenvironment created by...

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Bibliographic Details
Main Authors: Hyeon Ryoo, Regina Giovanni, Hannah Kimmel, Ishita Jain, Gregory H. Underhill
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202303128