Evaluation of the specificity of an intradermal test with recombinant tuberculosis allergen in Bacillus Calmette–Guérin-vaccinated healthy volunteers

Evaluation of the specificity of an intradermal test with recombinant tuberculosis allergen in Bacillus Calmette–Guérin-vaccinated healthy volunteers

IntroductionThe tuberculin skin test has significant limitations for use in individuals vaccinated with BCG. The presence in the genome of Mycobacterium tuberculosis of the RDI region, which is absent in the genome of Mycobacterium bovis BCG and most non-tuberculous mycobacteria, made it possible to...

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Main Authors: Irina A. Vasilyeva, Valentina A. Aksenova, Alexey V. Kazakov, Yulia Y. Kiseleva, Andrey O. Maryandyshev, Elena N. Dolzhenko, Anna V. Abramchenko, Nadejda I. Klevno, Konstantin A. Glebov, Anna E. Panova, Larisa Y. Petrova, Elena G. Sheikis, Inna V. Seregina, Elena I. Nikishova, Natalia P. Doktorova, Anastasia G. Samoilova
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Medicine
Subjects:
tuberculosis
specificity
Diaskintest®
skin test
recombinant tuberculosis allergen
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1042461/full

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https://www.frontiersin.org/articles/10.3389/fmed.2023.1042461/full

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