Profiling protein expression in circulating tumour cells using microfluidic western blotting

Circulating tumour cells (CTCs) are rare cells found in the blood of certain cancer patients. Here, the authors develop a cytometry tool that appends a microfluidic western blot to a CTC isolation workflow and apply it to profile a panel of proteins in single CTCs isolated from ER+ breast cancer pat...

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Bibliographic Details
Main Authors: Elly Sinkala, Elodie Sollier-Christen, Corinne Renier, Elisabet Rosàs-Canyelles, James Che, Kyra Heirich, Todd A. Duncombe, Julea Vlassakis, Kevin A. Yamauchi, Haiyan Huang, Stefanie S. Jeffrey, Amy E. Herr
Format: Article
Language:English
Published: Nature Portfolio 2017-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14622