How bulk fluid renewal can affect in vitro drug release from PLGA implants: Importance of the experimental set-up

The aim of this study was to better understand the potential impact of partial vs. complete renewal of the bulk fluid during drug release measurements from poly (lactic-co-glycolic acid) (PLGA)-based implants. A “standard experimental set-up”, in which the implants were directly exposed to well agit...

Full description

Bibliographic Details
Main Authors: C. Bassand, L. Benabed, J. Freitag, J. Verin, F. Siepmann, J. Siepmann
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:International Journal of Pharmaceutics: X
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590156722000202