Toward a network model of MHC class II-restricted antigen processing

Toward a network model of MHC class II-restricted antigen processing

The standard model of Major Histocompatibility Complex class II (MHCII)-restricted antigen processing depicts a straightforward, linear pathway: Internalized antigens are converted into peptides that load in a chaperone dependent manner onto nascent MHCII in the late endosome, the complexes subseque...

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Bibliographic Details
Main Authors: Laurence C Eisenlohr, Michael A Miller, Asha Purnima Veerappan Ganesan
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-12-01
Series:Frontiers in Immunology
Subjects:
Antigen Presentation
review
antigen processing
endogenous
MHC class II
alternative processing
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00464/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00464/full

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