Borneol Ester Derivatives as Entry Inhibitors of a Wide Spectrum of SARS-CoV-2 Viruses

Borneol Ester Derivatives as Entry Inhibitors of a Wide Spectrum of SARS-CoV-2 Viruses

In the present work we studied the antiviral activity of the home library of monoterpenoid derivatives using the pseudoviral systems of our development, which have glycoproteins of the SARS-CoV-2 virus strains Wuhan and Delta on their surface. We found that borneol derivatives with a tertiary nitrog...

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Bibliographic Details
Main Authors: Olga I. Yarovaya, Dmitriy N. Shcherbakov, Sophia S. Borisevich, Anastasiya S. Sokolova, Maxim A. Gureev, Edward M. Khamitov, Nadezda B. Rudometova, Anastasiya V. Zybkina, Ekaterina D. Mordvinova, Anna V. Zaykovskaya, Artem D. Rogachev, Oleg V. Pyankov, Rinat A. Maksyutov, Nariman F. Salakhutdinov
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Viruses
Subjects:
SARS-CoV-2
coronavirus surface protein S-spike
pseudoviral system
terpene
borneol
molecular dynamics
Online Access:https://www.mdpi.com/1999-4915/14/6/1295

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https://www.mdpi.com/1999-4915/14/6/1295

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