Diamidines versus Monoamidines as Anti-Pneumocystis Agents: An in Vivo Study

Diamidines versus Monoamidines as Anti-Pneumocystis Agents: An in Vivo Study

Some compounds articulated around a piperazine or an ethylenediamine linker have been evaluated in vitro to determine their activity in the presence of a 3T6 fibroblast cell line and an axenic culture of Pneumocystis carinii, respectively. The most efficient antifungal derivatives, namely N,N′-bis(b...

Full description

Bibliographic Details
Main Authors: El-Moukhtar Aliouat, Eduardo Dei-Cas, Anna Martinez, Jean Jacques Vanden Eynde, Sébastien Boutry, Isabelle Mahieu, Delphine Forge, Claire Pinçon, Dimitri Stanicki, Muriel Pottier, Nausicaa Gantois
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Series:Pharmaceuticals
Subjects:
Pneumocystis
pentamidine
diamidine
Online Access:http://www.mdpi.com/1424-8247/6/7/837

Internet

http://www.mdpi.com/1424-8247/6/7/837

Similar Items