Interim data monitoring to enroll higher-risk participants in HIV prevention trials

<p>Abstract</p> <p>Background</p> <p>Lower-than-expected incidence of HIV undermines sample size calculations and compromises the power of a HIV prevention trial. We evaluated the effectiveness of interim monitoring of HIV infection rates and on-going modification of re...

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Bibliographic Details
Main Authors: Umo-Otong John, Otusanya Sakiru, Ogunsola Folasade, Obunge Orikomaba, Halpern Vera, Wang Chin-Hua, Mehta Neha
Format: Article
Language:English
Published: BMC 2009-06-01
Series:BMC Medical Research Methodology
Online Access:http://www.biomedcentral.com/1471-2288/9/44