Interim data monitoring to enroll higher-risk participants in HIV prevention trials
<p>Abstract</p> <p>Background</p> <p>Lower-than-expected incidence of HIV undermines sample size calculations and compromises the power of a HIV prevention trial. We evaluated the effectiveness of interim monitoring of HIV infection rates and on-going modification of re...
Main Authors: | Umo-Otong John, Otusanya Sakiru, Ogunsola Folasade, Obunge Orikomaba, Halpern Vera, Wang Chin-Hua, Mehta Neha |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-06-01
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Series: | BMC Medical Research Methodology |
Online Access: | http://www.biomedcentral.com/1471-2288/9/44 |
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