Precision-cut lung slices as an ex vivo model to study Pneumocystis murina survival and antimicrobial susceptibility

Precision-cut lung slices as an ex vivo model to study Pneumocystis murina survival and antimicrobial susceptibility

ABSTRACTPneumocystis pneumonia (PCP) is a serious fungal lung infection caused by Pneumocystis jirovecii in immunosuppressed individuals. The lack of viable in vitro/ex vivo PCP models has greatly hindered the progress in studying the biology of these fungi, the host/pathogen interactions, as well a...

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Bibliographic Details
Main Authors: Ferris T. Munyonho, Robert D. E. Clark, Dong Lin, Mst Shamima Khatun, Dora Pungan, Guixiang Dai, Jay K. Kolls
Format: Article
Language:English
Published: American Society for Microbiology 2024-01-01
Series:mBio
Subjects:
Pneumocystis pneumonia
Pneumocystis murina
PCLS
Online Access:https://journals.asm.org/doi/10.1128/mbio.01464-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01464-23

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