Identification and validation of core genes for type 2 diabetes mellitus by integrated analysis of single-cell and bulk RNA-sequencing

Identification and validation of core genes for type 2 diabetes mellitus by integrated analysis of single-cell and bulk RNA-sequencing

Abstract Background The exact mechanisms of type 2 diabetes mellitus (T2DM) remain largely unknown. We intended to authenticate critical genes linked to T2DM progression by tandem single-cell sequencing and general transcriptome sequencing data. Methods T2DM single-cell RNA-sequencing data were subm...

Full description

Bibliographic Details
Main Authors: Tingting Yang, Chaoying Yan, Lan Yang, Jialu Tan, Shiqiu Jiang, Juan Hu, Wei Gao, Qiang Wang, Yansong Li
Format: Article
Language:English
Published: BMC 2023-09-01
Series:European Journal of Medical Research
Subjects:
Type 2 diabetes mellitus
Single-cell sequencing
Traditional transcriptome sequencing
CDKN1C
DLK1
Online Access:https://doi.org/10.1186/s40001-023-01321-1

Internet

https://doi.org/10.1186/s40001-023-01321-1

Similar Items