New Horizons in Metastatic Colorectal Cancer: Prognostic Role of CD44 Expression

New Horizons in Metastatic Colorectal Cancer: Prognostic Role of CD44 Expression

Background: The transmembrane glycoprotein CD44, the major hyaluronan (HA) receptor, has been proven to regulate cell growth, survival, differentiation, and migration. It is therefore widely considered to be involved in carcinogenesis. Its role as a new therapeutic target in solid tumors is under ev...

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Bibliographic Details
Main Authors: Pina Ziranu, Valentina Aimola, Andrea Pretta, Marco Dubois, Raffaele Murru, Nicole Liscia, Flaviana Cau, Mara Persano, Giulia Deias, Enrico Palmas, Francesco Loi, Marco Migliari, Valeria Pusceddu, Marco Puzzoni, Eleonora Lai, Stefano Cascinu, Gavino Faa, Mario Scartozzi
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
metastatic colorectal cancer
biomarkers
CD44 expression
cancer stem cells
Online Access:https://www.mdpi.com/2072-6694/15/4/1212

Internet

https://www.mdpi.com/2072-6694/15/4/1212

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