Metagenomic Next-Generation Sequencing of Cerebrospinal Fluid for the Diagnosis of Cerebral Aspergillosis

Purpose: Cerebral aspergillosis (CA) is a rare but often fatal, difficult-to-diagnose, opportunistic infection. The utility of metagenomic next-generation sequencing (mNGS) for diagnosis of CA is unclear. We evaluated the usefulness of mNGS of the cerebrospinal fluid (CSF) for the diagnosis of CA.Me...

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Main Authors: Xiao-Wei Xing, Su-Fei Yu, Jia-Tang Zhang, Rui-Shu Tan, Yu-Bao Ma, Xia Tian, Rong-Fei Wang, Guo-En Yao, Fang Cui, Qiu-Ping Gui, Sheng-Yuan Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.787863/full